Plasma metabolomics reveals the efficacy of a mycotoxin-deactivating product in early-lactation dairy cows fed a Fusarium-contaminated diet

Published: 30 June 2025| Version 1 | DOI: 10.17632/vxn87nnkx4.1
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Description

Supplementary Table S1. Excel file containing the following sheets: a) plasma metabolites annotated by UHPLC-HRMS analysis; b) RSD (%) of the different annotated metabolites in pooled QC samples; c) VIP discriminant compounds included in the significant metabolomic pathways and resulting from the pairwise comparison "MDP vs MTX"; d) VIP discriminant compounds included in the significant metabolomic pathways and resulting from the pairwise comparison "MDP vs CTR"; e) VIP discriminant compounds included in the significant metabolomic pathways and resulting from the pairwise comparison "MTX vs CTR"; f) Exclusive VIP discriminant compounds for the different pairwise comparisons and resulting from the Venn diagram.

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Steps to reproduce

Data on plasma metabolites were obtained using an UHPLC system coupled with an Orbitrap Q-Exactive Focus as mass spectrometer (Thermo). The generated mass features were then elaborated on the software MS-DIAL (version 4.90) against the Bovine Metabolome Database for putative annotation according to a level 2 of confidence.

Institutions

Universita Cattolica del Sacro Cuore

Categories

Dairy Cattle, Untargeted Metabolomics

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